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Journal articles
What modulates animal longevity ? Fast and slow aging in bivalves as a model for the study of lifespan
Abstract : Delineating the physiological and biochemical causes of aging process in the animal kingdom is a highly active area of research not only because of potential benefits for human health but also because aging process is related to life history strategies (growth and reproduction) and to responses of organisms to environmental conditions and stress. In this synthesis, we advocate studying bivalve species as models for revealing the determinants of species divergences in maximal longevity. This taxonomic group includes the longest living metazoan on earth (Arctica islandica), which insures the widest range of maximum life span when shorter living species are also included in the comparative model. This model can also be useful for uncovering factors modulating the pace of aging in given species by taking advantages of the wide disparity of lifespan among different populations of the same species. For example, maximal lifespan in different populations of A islandica range from approximately 36 years to over 500 years. In the last 15 years, research has revealed that either regulation or tolerance to oxidative stress is tightly correlated to longevity in this group which support further investigations on this taxon to unveil putative mechanistic links between Reactive Oxygen Species and aging process.
https://hal-sde.archives-ouvertes.fr/hal-01689743
Contributor : Nathalie Lyvet <>
Submitted on : Monday, January 22, 2018 - 2:21:20 PM
Last modification on : Tuesday, March 17, 2020 - 3:20:46 AM
Contributor : Nathalie Lyvet <>
Submitted on : Monday, January 22, 2018 - 2:21:20 PM
Last modification on : Tuesday, March 17, 2020 - 3:20:46 AM
