Uncoupling effect of palmitate is exacerbated in skeletal muscle mitochondria of sea-acclimatized king penguins (Aptenodytes patagonicus)

Abstract : In king penguin juveniles, the environmental transition from a terrestrial to a marine habitat, occurring at fledging, drastically stimulates lipid catabolism and the remodelling of muscle mitochondria to sustain extensive swimming activity and thermoregulation in the cold circumpolar oceans. However, the exact nature of these mechanisms remains only partially resolved. Here we investigated, in vitro, the uncoupling effect of increasing doses of fatty acids in pectoralis muscle intermyofibrillar mitochondria isolated, either from terrestrial never-immersed or experimentally cold water immersed pre-fledging king penguins or from sea-acclimatized fledged penguins. Mitochondria exhibited much greater palmitate-induced uncoupling respiration and higher maximal oxidative capacity after acclimatization to marine life. Such effects were not reproduced experimentally after repeated immersions in cold water, suggesting that the plasticity of mitochondrial characteristics may not be primarily driven by cold exposure per se but by other aspects of sea acclimatization. Keywords
Type de document :
Article dans une revue
Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, Elsevier, 2017, 211, pp.56-60. 〈10.1016/j.cbpa.2017.06.009〉
Liste complète des métadonnées

https://hal-sde.archives-ouvertes.fr/hal-01548837
Contributeur : Nathalie Lyvet <>
Soumis le : mercredi 28 juin 2017 - 10:34:35
Dernière modification le : mardi 24 avril 2018 - 13:31:38

Identifiants

Collections

Citation

Benjamin Rey, Claude Duchamp, Damien Roussel. Uncoupling effect of palmitate is exacerbated in skeletal muscle mitochondria of sea-acclimatized king penguins (Aptenodytes patagonicus). Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, Elsevier, 2017, 211, pp.56-60. 〈10.1016/j.cbpa.2017.06.009〉. 〈hal-01548837〉

Partager

Métriques

Consultations de la notice

171